Referencias Científicas
Base de evidencia del protocolo · Estudios revisados por pares
Las afirmaciones y recomendaciones del Truco del Café están fundamentadas en investigación científica publicada en revistas médicas y nutricionales de referencia. A continuación presentamos los estudios que sustentan los principios del protocolo.
Cafeína y Termogénesis
Efecto del café sobre el gasto energético y la quema de grasa
Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers
Dulloo AG, Geissler CA, Horton T, Collins A, Miller DS.
American Journal of Clinical Nutrition, 1989; 49(1): 44–50.
Metabolic effects of caffeine in humans: lipid oxidation or futile cycling?
Acheson KJ, Zahorska-Markiewicz B, Pittet P, Anantharaman K, Jéquier E.
American Journal of Clinical Nutrition, 1980; 33(5): 989–997.
Effects of caffeine on energy metabolism, heart rate, and methylxanthine metabolism in lean and obese women
Bracco D, Ferrarra JM, Arnaud MJ, Jéquier E, Schutz Y.
American Journal of Physiology, 1995; 269(4 Pt 1): E671–678.
Ácido Clorogénico del Café
Compuestos bioactivos del café y su acción metabólica
The effect on body weight and composition in overweight subjects of green coffee extract
Thom E.
Journal of International Medical Research, 2007; 35(6): 900–908.
Randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects
Vinson JA, Burnham BR, Nagendran MV.
Diabetes, Metabolic Syndrome and Obesity, 2012; 5: 21–27.
The use of green coffee extract as a weight loss supplement: a systematic review and meta-analysis
Onakpoya I, Terry R, Ernst E.
Gastroenterology Research and Practice, 2011; 2011: 382852.
Catecinas y Oxidación de Grasas
Compuestos del café y té en la movilización de grasa corporal
The effects of catechin rich teas and caffeine on energy expenditure and fat oxidation: a meta-analysis
Hursel R, Viechtbauer W, Dulloo AG, et al.
Obesity Reviews, 2011; 12(7): e573–581.
Caffeine intake increases plasma ketones: an acute metabolic study in humans
Vandenberghe C, St-Pierre V, Courchesne-Loyer A, et al.
Canadian Journal of Physiology and Pharmacology, 2017; 95(4): 455–458.
Tejido Adiposo Pardo (BAT)
Activación del tejido graso termogénico en adultos
Identification and importance of brown adipose tissue in adult humans
Cypess AM, Lehman S, Williams G, et al.
New England Journal of Medicine, 2009; 360(15): 1509–1517.
Cold-activated brown adipose tissue in healthy men
van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM, et al.
New England Journal of Medicine, 2009; 360(15): 1500–1508.
Caffeine increases sympathetic neurotransmitter release and enhances thermogenesis via brown adipose tissue activation
Velickovic K, Wayne D, Leija HAL, et al.
Scientific Reports, 2019; 9(1): 2049.
Adaptación Metabólica y Dietas
Por qué las dietas restrictivas no funcionan a largo plazo
Changes in energy expenditure resulting from altered body weight
Leibel RL, Rosenbaum M, Hirsch J.
New England Journal of Medicine, 1995; 332(10): 621–628.
Long-term persistence of hormonal adaptations to weight loss
Sumithran P, Prendergast LA, Delbridge E, et al.
New England Journal of Medicine, 2011; 365(17): 1597–1604.
Cortisol, Estrés y Peso en Mujeres
Relación entre el estrés hormonal y la acumulación de grasa abdominal
Stress and body shape: stress-induced cortisol secretion is consistently greater among women with central fat
Epel ES, McEwen B, Seeman T, et al.
Psychosomatic Medicine, 2000; 62(5): 623–632.
Habitual coffee consumption and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a dose-response meta-analysis
Ding M, Bhupathiraju SN, Chen M, van Dam RM, Hu FB.
Circulation, 2014; 129(6): 643–659.
Mantenimiento del Peso
Estrategias sostenibles para no recuperar el peso perdido
Weight management using a meal replacement strategy: meta and pooling analysis from six studies
Heymsfield SB, van Mierlo CA, van der Knaap HC, Heo M, Frier HI.
International Journal of Obesity, 2003; 27(5): 537–549.
Coffee consumption and risk of type 2 diabetes: a dose-response meta-analysis of prospective studies
Ding M, Bhupathiraju SN, Satija A, van Dam RM, Hu FB.
Nutrition, Metabolism and Cardiovascular Diseases, 2014; 24(5): 468–475.
Los estudios listados son de acceso público y pueden verificarse en PubMed (pubmed.ncbi.nlm.nih.gov) utilizando los identificadores PMID indicados. Los resultados individuales pueden variar.